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The 14 Best Vegetarian Gluten-Free Spots in Des Moines

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By Gluten Free Eats' gluten-free community

Updated Jun 2025

01
Louie's Wine Dive

Louie's Wine Dive

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Celiac friendly

4040 University Ave suite a, Des Moines, IA 50311, USA

Wine BarCocktailsAmericanBrunchGF OptionsAllergen FriendlyBreakfastDairy Free OptionsDinnerKid FriendlyLunchOutdoor SeatingSeafoodTake AwayVegan OptionsVegetarian OptionsDedicated GF FryerBeerCeliac FriendlyOpen LateDeliveryPet FriendlyRestaurant

A favorite local spot with a vibrant patio and a diverse menu that keeps everyone happy, offering fun shareable bites and tasty drinks.

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This place is a gluten-free haven.

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02
Fresko

Fresko

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Celiac friendly

909 Locust St Ste. 103, Des Moines, IA 50309, USA

CocktailsBrunchGF OptionsAllergen FriendlyBreakfastDairy Free OptionsDeliveryDinnerKid FriendlyOpen Late NightLunchTake AwayVegan OptionsVegetarian OptionsDedicated GF FryerBread ItemsBurgersDessertsSandwichesTacosCeliac FriendlyRestaurant

With a modern vibe and unique specials, this Des Moines hotspot is perfect for everything from brunch to celebrations, delivering consistently good experiences.

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Mijo Martinez (Mijo Martinez)

My chicken chiabatta sandwich was a bit dry and the food selection was limited, but they did have substantial gluten free options. The setting and staff were very nice, making it an overall excellent experience.

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03
Bar Nico

Bar Nico

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100% Dedicated Gluten-Free

428 E Locust St, Des Moines, IA 50309, USA

GF OptionsMexicanCocktailsAllergen FriendlyDinnerOpen Late NightLunchTake AwayVegetarian OptionsVegan OptionsTacos100% GFCeliac FriendlySeparate GF MenuSeparate OvenKnowledgeable StaffDedicated GF Kitchen SpaceDessertsDedicated GF FryerBreakfastBrunchDeliveryPet FriendlyKid FriendlyOutdoor Seating

Experience a culinary gem with fresh, flavorful dishes, creative options, and top-notch cocktails in a vibrant setting that's perfect for any occasion.

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Emily Onomatopoeia

O.M.G. 100% gluten free kitchen AND the food was absolutely amazing!! Our waitress was super friendly! I would give more than 5 stars if I could!!!

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Dedicated gluten-free menu
04
Thistle's Summit

Thistle's Summit

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100% Dedicated Gluten-Free

340 SW 5th St #122, Des Moines, IA 50309, USA

GF OptionsCeliac FriendlyVegan OptionsAllergen FriendlyBakeryBreakfastBrunchDairy Free OptionsDeliveryKid FriendlyTake AwayVegetarian OptionsDesserts100% GFSeparate GF MenuSeparate OvenKnowledgeable StaffDedicated GF Kitchen Space

Experience a nostalgic journey with creative baked goods that evoke childhood memories, plus a charming apothecary upstairs filled with unique finds.

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Natasha Huffman

This bakery is vegan and gluten free, and everything I've had from here is absolutely amazing! The people working are always warm and welcoming as well, definitely recommend:) and don't forget to check out the antiques upstairs!

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Dedicated gluten-free menu
05
Americana

Americana

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Celiac friendly

1312 Locust St, Des Moines, IA 50309, USA

AmericanBrunchGF OptionsAllergen FriendlyBreakfastDairy Free OptionsDeliveryDinnerOpen Late NightLunchTake AwayVegan OptionsVegetarian OptionsDedicated GF FryerCiderDessertsCeliac FriendlyKnowledgeable StaffKid FriendlyPancakesBread ItemsSandwichesCocktails

A lively spot with a vast menu and unique stations, perfect for groups but challenging for those with mobility issues due to stair access.

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Jennifer VanSickle

Love it every time. Good atmosphere and I'm pretty find if the gluten sensitive choices. Well worth it.

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