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The 35 Best Gluten-Free Spots in Florence

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By Gluten Free Eats' gluten-free community

Updated May 2025

01
Mellow Mushroom Florence

Mellow Mushroom Florence

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120 Dunbarton Dr, Florence, SC 29501, USA

LunchDinnerVeganOpen LatePizzaDeliveryTake AwayPet FriendlyOutdoor SeatingKid FriendlyBread ItemsRestaurant
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Vicki Elmore

Elmo is always my server. She always does an excellent job. She makes sure I get gluten free options.

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02
Eliza's Vegan Café

Eliza's Vegan Café

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1832b W Lucas St, Florence, SC 29501, USA

LunchDinnerVeganDeliveryTake AwayOutdoor SeatingKid Friendly
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Nel Husband

This cafe is simply exceptional. Thank goodness for the sign on US151, or I would never have known to stop by. The last thing I expected in rural SC was an outstanding vegan meal. Without question, the best vegan burger I’ve ever had. The best vegan and gluten-free burger bun I’ve ever had! Soft! Beautiful-tasting! And the burger itself? Bloody incredible. The special sauce was the kicker. Everything about this burger was uber delicious. The fries were excellent as well - perfect size, perfect handcooked taste. The meal was so large I could have taken some back to the truck with me but I wanted to eat it all in the restaurant because I just loved being there. A very safe place for trans people 🏳️‍⚧️Great music!! Wonderful, wise messages on the wall from the cafe’s namesake, Eliza Jenkins. Her granddaughter Markeyshi, the owner (pictured), and her talented cook gave me such a warm welcome and a restaurant experience that I will always remember. Thank you so much 🧡 Worth driving for from Montana. Worth travelling from Aotearoa NZ 🇳🇿 for, for that matter! Giving Eliza’s a 500-star recommendation. Hope I can return very 🔜

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03
Ruby Tuesday

Ruby Tuesday

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1550 American Dr, Florence, SC 29505, USA

LunchDinnerOpen LateAmericanDeliveryTake AwayKid Friendly
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Andy Pigge

Friend ly. Staff fast service great gluten free hamburger bun

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04
Buddy's

Buddy's

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Celiac friendly

2519b W Palmetto St, Florence, SC 29501, USA

Celiac FriendlyLunchDinnerDairy FreeVeganVegetarianBread ItemsBurgersKid FriendlyTake AwayPet FriendlyOutdoor SeatingBreakfastRestaurantDedicated GF Fryer
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Leslie Young

Great food. Great people. Loved the gluten free bun option. Kids loved it. Will definitely be back next time we travel south!

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05
Olive Garden Italian Restaurant

Olive Garden Italian Restaurant

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Accommodating

2901 W Radio Dr, Florence, SC 29501, USA

LunchDinnerItalianMediterraneanDeliveryTake AwayKid Friendly
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Lewis rich

The gluten-free pasta was great I had the mushroom sauce absolutely wonderful

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