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The 1 Best Gluten-Free Spots in Hyannis

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By Gluten Free Eats' gluten-free community

Updated Apr 2025

01
Pizza Barbone

Pizza Barbone

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390 Main St, Hyannis, MA 02601, USA

PizzaGF OptionsDairy Free OptionsDinnerKid FriendlyLunchOutdoor SeatingTake AwayVegan OptionsVegetarian OptionsDelivery
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This is our go to pizzeria when visiting the Cape! The restaurant is beautiful and the staff is always attentive and friendly. They have a nice selection of specialty pizzas. I have a gluten sensitivity so I ordered the Pistachio Pesto pizza on GF crust and it was wonderful! My husband ordered the forest mushroom and my daughter had a classic cheese pizza. You can't beat their weekday lunch special! A pizza, salad and beverage for $16! Such a steal for a place this good!

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02
Not Your Average Joe's

Not Your Average Joe's

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412 Iyannough Rd, Hyannis, MA 02601, USA

GrillAmericanPizzaGF OptionsAllergen FriendlyDairy Free OptionsDinnerKid FriendlyLunchTake AwayBeerBread ItemsBurgersSandwichesBrunchOpen LateDeliveryPet FriendlyOutdoor Seating
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Danielle Hardie (Dani)

I recently visited Not Your Average Joe's and was pleased to find a variety of gluten-free options on the menu. The food was tasty, but unfortunately, the prices didn't quite match the quality and portion sizes. I felt it was a bit overpriced for what we received. The service was just okay. Our server seemed friendly, but when we asked for soda refills, they never arrived. This was particularly surprising since we visited mid-afternoon and the restaurant wasn't busy. Overall, I'd give Not Your Average Joe's 3.5 stars out of 5. While I appreciated the gluten-free options and enjoyed the food, the value and service didn't quite live up to my expectations. Perhaps with some adjustments, I'd consider returning and bumping up my rating.

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03
Bread + Roses Bookstore and Café

Bread + Roses Bookstore and Café

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302 Main St, Hyannis, MA 02601, USA

BreakfastLunchBrunchVeganCafeDeliveryTake AwayPet FriendlyOutdoor SeatingKid FriendlyRestaurantBakery
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John Davis

Delicious vegan treats and some good gluten free options. Nice selection of books too!

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04
Sam Diego's Mexican Cookery and Bar

Sam Diego's Mexican Cookery and Bar

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Accommodating

950 Iyannough Rd, Hyannis, MA 02601, USA

LunchDinnerOpen LateMexicanAmericanDeliveryTake AwayOutdoor SeatingKid FriendlyBarDedicated GF FryerPet Friendly
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Karen Melo Ticas, CFP

(Note: I write these reviews in part for my own nationwide business clients, for travel and activity inspiration. Follow me for more! I’m a financial planner - CFP®️practitioner - with a focus on retirement wealth strategies, primarily serving business women and LGBTQ individuals. #VirtualPlanningCraftedWithCare®️) If you’re in the area and looking for a causal place for some hearty food, stop in here. My rating is based on my expectations of a casual hangout establishment. And it met this expectation with no problems. First, they have a big parking area with an equally large dining area. Then, our server Melissa was just great. Friendly, attentive, and helpful in terms of helping me navigate a gluten allergy. They even have a gluten free menu which is very convenient. The food overall was good. Large portions and served piping hot which is what I like. We weren’t looking for anything gourmet but rather just a hearty meal after spending a while driving into the area. I had a fruit flavored skinny margarita which is hard to find. The prices were in line with similar places. The establishment is suitable for all ages, families, singles, couples and retirees. I imagine it’s LGBTQ friendly given that it’s in the Cape. We liked it and we would return the next time we’re visiting.

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05
Grilled Cheese Gallery

Grilled Cheese Gallery

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Celiac friendly

569 Main St, Hyannis, MA 02601, USA

LunchGF OptionsDairy Free OptionsDinnerKid FriendlyOutdoor SeatingTake AwayVegan OptionsVegetarian OptionsDedicated GF FryerBread ItemsFriesSandwichesCeliac FriendlyCasualDelivery
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Daniel Kercuku

I had the best gluten free grilled cheese sandwich ever it was so good.They can make every grill cheese sandwich on a gluten free bread 🥳and the staff was very friendly,definitely recommend