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The 8 Best Gluten-Free Sandwich Spots in Charleston

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By Gluten Free Eats' gluten-free community

Updated Apr 2025

01
Annie O' Love's Cookie Cafe

Annie O' Love's Cookie Cafe

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100% Dedicated Gluten-Free

1901 Ashley River Rd, Charleston, SC 29407, USA

Celiac FriendlyVegan OptionsGF OptionsAllergen FriendlyBakeryBreakfastBrunchCoffeeDairy Free OptionsDeliveryDinnerKid FriendlyLunchTake AwayVegetarian OptionsKnowledgeable StaffBread ItemsDessertsSandwichesWaffles / Crepes100% GFSeparate GF MenuDedicated GF Kitchen SpacePancakesPet Friendly
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Chimkin lil

Dedicated gluten free and vegan? What more could I ask for. Literally everything on the menu I tried was amazing. We even went twice in the weekend we were there. Staff were super helpful, friendly and were able to make lots of recommendations.

02
Heavy's Barburger

Heavy's Barburger

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Celiac friendly

1137 Morrison Dr, Charleston, SC 29403, USA

LunchDinnerDairy FreeAllergen FriendlyVeganVegetarianDedicated GF FryerCeliac FriendlyTake AwayBread ItemsBurgersFriesSandwichesBeerKid FriendlyOutdoor SeatingCasualPet FriendlyDessertsCocktailsDeliveryRestaurantOpen LateBar100% GF
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Fontaine Weyman

Definitely one of the best burgers in town and the best gluten-free bun in town besides Edmund’s Oast. Only bummer is the gluten-free bun is a three dollar up charge, but the burger itself is incredibly flavorful and delicious. Service was great and fast. Will definitely be returning.

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Dedicated gluten-free menu
03
Brown Dog Deli

Brown Dog Deli

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Accommodating

225 Calhoun St, Charleston, SC 29401, USA

GF OptionsAllergen FriendlyDairy Free OptionsDeliveryKid FriendlyLunchOutdoor SeatingTake AwayVegan OptionsVegetarian OptionsBread ItemsSandwichesAmericanBreakfastDinnerBrunchRestaurant
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Philip Mager

Great sandwiches. Great atmosphere. Gluten free options are fantastic. Super friendly and helpful staff.

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04
East Bay Deli - Downtown

East Bay Deli - Downtown

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Gluten-free options

334 E Bay St Ste H, Charleston, SC 29401, USA

Salad BarLunchGF OptionsKid FriendlyBread ItemsSandwichesDeliveryTake AwayDessertsRestaurantBreakfast
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Billy Blake

It's difficult to find great delis in the south, but this is definitely one of them. They offer a wide variety of options, including Gluten Free bread. They are open for lunch and early dinner, and there is ample parking available in front of the deli. Another great aspect is that they have plenty of seating. Overall, it's a fantastic deli that ticks all the boxes.

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05
Ruby Sunshine

Ruby Sunshine

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Accommodating

171 E Bay St, Charleston, SC 29401, USA

CocktailsBrunchBreakfastGF OptionsKid FriendlyOutdoor SeatingTake AwayBread ItemsSandwichesBurgersLunchAmericanDeliveryPet Friendly
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Amber Easterling

A must for breakfast or brunch! They have a gluten friendly menu if you ask. They have a dedicated cooking space and fryer for GF food and they offer GF bread for burgers/sandwiches. The French toast is amazing!!

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GF options marked