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The 39 Best Gluten-Free Sandwich Spots in South Carolina

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By Gluten Free Eats' gluten-free community

Updated Dec 2024

01
Nose Dive

Nose Dive

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Celiac friendly

116 S Main St, Greenville, SC 29601, USA

BrunchGF OptionsAllergen FriendlyBreakfastDinnerKid FriendlyLunchOutdoor SeatingTake AwaySandwichesCocktailsBread ItemsDedicated GF FryerBeerBurgersDessertsFish & ChipsFriesOpen LateDeliveryCeliac Friendly
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Paige Bowser

The food and service were amazing. My husband can’t have gluten (non celiac gluten intolerance) we were happy that they offered a gluten free bun option and asked about allergens. I really enjoyed the sweet potato fries. They were perfect. We enjoyed sitting outdoor and people watching.

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GF options marked
02
Annie O' Love's Cookie Cafe

Annie O' Love's Cookie Cafe

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100% Dedicated Gluten-Free

1901 Ashley River Rd, Charleston, SC 29407, USA

Celiac FriendlyVegan OptionsGF OptionsAllergen FriendlyBakeryBreakfastBrunchCoffeeDairy Free OptionsDeliveryDinnerKid FriendlyLunchTake AwayVegetarian OptionsKnowledgeable StaffBread ItemsDessertsSandwichesWaffles / Crepes100% GFSeparate GF MenuDedicated GF Kitchen SpacePancakesPet Friendly
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Annie's Cafe of Sweet Abundance was the best find in our gluten free, vegan food search history. We absolutely loved everything on the menu. My daughter got the strawberry shortcake, which came in a glass jar, and we got several of the decadent cookies on each visit. The oatmeal cream sandwich cookie is divine! The menu is incredible, so I'm posting it for all to see and marvel over the creative ideas here. For those of eating gluten free and avoiding dairy and eggs, this is the answer to your prayers. We'll be back every time we visit Charleston. Thank you!

03
LuLu's North Myrtle Beach

LuLu's North Myrtle Beach

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Celiac friendly

4954 Hwy 17 S, North Myrtle Beach, SC 29582, USA

GF OptionsSeafoodAllergen FriendlyDairy Free OptionsDinnerKid FriendlyLunchOutdoor SeatingTake AwayVegan OptionsVegetarian OptionsDedicated GF Kitchen SpaceDedicated GF FryerBeerBread ItemsBurgersTacosCeliac FriendlyMexicanDessertsSandwichesDeliveryCasualBreakfastBrunchPet FriendlyBarRestaurant
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Joey B. Was our server he was AMAZING! Took time to tell us what was the best things on the menu, was very knowledgeable, and extremely personable. When I said I was GF he asked right away if I was a Celiac and went above and beyond to accommodate my needs and was extremely knowledgeable. He truly was one of the best servers we have ever had. The food was amazing and we definitely will be back!

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Dedicated gluten-free menu
04
Grill Marks - Main St. Greenville

Grill Marks - Main St. Greenville

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Celiac friendly

209 S Main St, Greenville, SC 29601, USA

GF OptionsBurgersDinnerPet FriendlyKid FriendlyLunchOutdoor SeatingTake AwayCeliac FriendlyGF MenuDedicated GF FryerFriesKnowledgeable StaffBread ItemsDessertsSandwichesBrunchDelivery
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Jordan Hunter

My husband is fully gluten free (celiac) and this place is the best! The entire menu is gluten free excluding a couple burger buns, but they have gluten free buns available at no up charge. My husband usually gets the fried chicken and I always have a burger. The haystack onion strings are something I dream about. Great food and great service!

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Dedicated gluten-free menu
05
Salty Brews Cafe

Salty Brews Cafe

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Celiac friendly

223 Sea Mountain Hwy, North Myrtle Beach, SC 29582, USA

Celiac FriendlyDedicated GF FryerBrunchLunchCafeDinnerBreakfastDairy FreeVegetarianBread ItemsBeerBurgersDessertsPastaSandwichesSushiTacosKid FriendlyOutdoor SeatingTake AwayPet FriendlyDeliveryRestaurant
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Bayside Chiropractic

Fabulous - creative - CELIAC SAFE- gluten free food with a fun beachy vibe. We had cocktails, Gutenberg beer, an ahi appetizer, the Seoul nachos and a decadent brownie/chocolate cookie/ice cream sundae for dessert. The owner came out to chat- his wife is celiac and they use a separate area in the kitchen for gf foods.

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Gluten-free options are marked