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The 10 Best Gluten-Free Restaurants in Downtown

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By Gluten Free Eats' gluten-free community

Updated Apr 2025

01
Sanaa's Gourmet Mediterranean

Sanaa's Gourmet Mediterranean

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401 E 8th St Unit 100, Sioux Falls, SD 57103, USA

Vegan OptionsGF OptionsAllergen FriendlyDairy Free OptionsDinnerKid FriendlyLunchMediterraneanTake AwayVegetarian OptionsBread ItemsDeliveryPet FriendlyRestaurant
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Amazing food. I’m gluten free so I ordered the shish tawook, Kufta kabob and lentil soup. I also ordered the hummus and olive tapenade which came with delicious GF bread. Everything was so delicious. FYI they no longer make GF fatayers.

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02
R Wine Bar & Kitchen

R Wine Bar & Kitchen

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Accommodating

322 E 8th St, Sioux Falls, SD 57103, USA

ItalianGF OptionsDairy Free OptionsDinnerOpen Late NightLunchOutdoor SeatingVegan OptionsVegetarian OptionsBread ItemsDeliveryTake AwayPet FriendlyRestaurant
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Nicole Madsen

Beautiful atmosphere with wonderful live music. The gluten free noodles were splendid and chicken very moist. The only semi-negative part is that the service took quite awhile, from ordering, to getting our food, to getting the check, we had to wait a very long time in between and spent close to 3 hours there.

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03
Crawford's

Crawford's

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Gluten-free options

214 S Phillips Ave, Sioux Falls, SD 57104, USA

DinnerBrunchOpen LateCocktailsDeliveryTake AwayOutdoor SeatingKid FriendlyPet FriendlyRestaurant
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Toni Lynn Rustand

We went to Crawford's last night for the 2nd time for our daughter's 16th birthday per her request. What a great place! We were lucky enough to get our same server, Natalia, who is beyond wonderful. Our daughter has a severe dairy allergy. Natalia made sure again to communicate with the chef about our daughters needs and the chef went above and beyond again to provide her with a safe and great meal! Then he also again went out of his way to provide her with an amazing desert that out did his last one! They even made sure my husband's gluten free food was safe for him as well! And when I say they were busy they were busy. If you have any type of allergy and want an amazing and safe place to eat. This is the place! These people are absolutely wonderful and really care about their customers! And just a heads up, call ahead and let them know of your needs.

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04
Josiah’s Coffeehouse & Café

Josiah’s Coffeehouse & Café

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104 W 12th St, Sioux Falls, SD 57104, USA

BreakfastLunchDinnerBrunchTake AwayPet FriendlyOutdoor SeatingKid FriendlyRestaurant
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Michelle Griep

Hankering for a huge plate of delicious breakfast? Skedaddle over to Josiah’s! The service was incredibly fast for my bacon, Gouda and carmelized onion omelette. They didn’t have gluten free bread but offered to give me more fruit instead, which was nice. Plenty of seating. Great place for the family.

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05
Chef Lance's on Phillips

Chef Lance's on Phillips

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Accommodating

431 N Phillips Ave, Sioux Falls, SD 57104, USA

DinnerDeliveryTake AwayKid FriendlyRestaurant
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Katie Dixon

This place is amazing. The food and atmosphere are wonderful. Very romantic feel to the restaurant. The food is a good variety and big portions. I love that they have many gluten free options as well! Everything is homemade and wonderful.

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