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The 17 Best Gluten-Free Restaurants in Downtown

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By Gluten Free Eats' gluten-free community

Updated Apr 2025

01
Osteria 166

Osteria 166

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166 Franklin St, Buffalo, NY 14202, USA

GF OptionsItalianPizzaDinnerLunchOutdoor SeatingTake AwayVegetarian OptionsVegan OptionsBread ItemsPastaSandwichesBrunchOpen LateDeliveryKid FriendlyRestaurant
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Amazing food, great service, and many gluten free options (pasta, pizza, etc.) The waitstaff was very knowledgeable on allergies and celiac disease and made sure to accommodate everyone. Plus, the food was absolutely amazing.

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02
Hearth + Press

Hearth + Press

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665 Main St, Buffalo, NY 14203, USA

LunchDinnerOpen LatePizzaDeliveryTake AwayRestaurant
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Tracey McDonald

We came from Atlanta and then walked 2.5 miles just to have this pizza. I had seen them on CBS mornings. They use flour from Italy which is what I use at home and doesn't bother my gluten intolerance. Worth every step!!!!!!

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03
Frankie Primo's +39

Frankie Primo's +39

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Accommodating

51 W Chippewa St, Buffalo, NY 14202, USA

LunchDinnerBrunchOpen LateItalianTake AwayOutdoor SeatingKid FriendlyRestaurant
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Connor Siem

They have gluten free options which always helps so celiac friendly! Tortellini soup was amazing and the pizza was solid.

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04
Graylynn

Graylynn

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537 Main St, Buffalo, NY 14203, USA

BreakfastLunchDinnerBrunchOpen LateDeliveryTake AwayOutdoor SeatingRestaurant
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maryjane meli

We all loved our food very much!!! Fantastic service, delicious unique flavors! Best creme brulee I've ever had! Only suggestion would be perhaps a few more gluten-free options, they were a little limited. Can't wait to go back!😋

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05
Public Espresso

Public Espresso

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391 Washington St, Buffalo, NY 14203, USA

BreakfastLunchBrunchBakeryCafeDeliveryTake AwayKid FriendlyDessertsRestaurant
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Jenna Morkisz

LOVE public espresso!! Best coffee in buffalo and great food. Wish they would bring back their gluten free donuts, they were amazing!

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