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The 5 Best Gluten-Free Italian Restaurants in Mission District

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By Gluten Free Eats' gluten-free community

Updated Apr 2025

01
Beretta Valencia

Beretta Valencia

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1199 Valencia St, San Francisco, CA 94110, USA

GF OptionsPizzaTake AwayDeliveryLunchOutdoor SeatingRestaurantBreakfastOpen LatePet FriendlyItalianBarCocktailsBrunchDinner
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Jinesh Jain

The drink "Fool me twice" was just something else!! Simply brilliant. And the gluten free pizza crust is delicious! Can't wait to come back!

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02
Flour + Water

Flour + Water

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2407 Harrison St, San Francisco, CA 94110, USA

GF Options100% Gluten FreeDinnerItalianPastaVegetarianOpen LateTake AwayLunchBrunch
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Ivy Eatmon

Our food was incredible! Worth the wait but recommend making reservations in advance if you can. Nonetheless, they have incredible gluten free crust (nothing I’ve had before) my partner also had a white pie and he loved it. The atmosphere is great, music is at a perfect volume, servers are extremely friendly and our server Jessie was so sweet! The hostess (Samantha) was also very accommodating and extremely friendly! Highly recommend this place! Must try.

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03
Bottega

Bottega

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1132 Valencia St, San Francisco, CA 94110, USA

LunchDinnerBrunchItalianAmericanCocktailsDeliveryTake AwayOutdoor SeatingKid FriendlyPet Friendly
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AN AUTHENTIC ITALIAN RESTAURANT. I say for 3 reasons: 1. All the staff are Italian 2. A member of my dinner party lived in Italy for several years, is fluent in Italian who also has an Italian husband and she confirmed this place screamed proper Italian 3. It gave me massive nostalgia of my recent trip to Italy a few months ago. I came with a party of 7 for my girlfriend's birthday. The manager Andrea was there at the front door to welcome us and quickly made small talk with our Italian speaking party members. We were sat upstairs in a balcony type seating which gave us a full view of the dining room - absolutely beautiful. Our waiter Marco was attentive and knowledgeable about the whole menu. We had a child with celiac so he quickly told us everything that she could eat and she loved every bite of it! All of the appetizers were amazing especially the meatballs, we had to order a second round. We ate the calamari, salads, and burrata which tasted amazing. We ordered individual pasta entrees of different varieties. Each member of my party could not stop talking about how delicious it was - IT WAS PROPER AL DENTE. Drinks are so reasonably priced. A glass of wine is $10-$14 which is SOO cheap in my opinion but all the wine tasted amazing - the bottles all cost about $40-$50 which is very affordable. To further compliment Marco, it was a busy evening but he never forgot a single thing we ordered even down to the modifications in a single persons entree. Even if his other duties created a longer wait time for our requests he continually reassured us that he would take care of it which he did. Desserts were phenomenal and they were nice to us to comp a dessert for the birthday member. We had the Tiramisu, Red Velvet Cake, and the Panna Cotta. Each one tasted amazing and we continually ate them despite how full we all were. Andrea was also so kind to bring the celiac child (Born in Italy and also speaks Italian) some gelato as it was gluten free and she was so thankful!! Andrea also gave us some Limoncello which tasted delicious! As someone who works for a high-end restaurant in San Francisco, Bottega truly is one the best restaurants I have had the pleasure of visiting. This place is 20/10 and I WILL be back as soon as I can. This is a repost of my yelp review, I wanted to make sure it was on both google and yelp.

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04
Penny Roma

Penny Roma

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777 Florida St #301, San Francisco, CA 94110, USA

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Luke Swartz

Penny Roma marries the former Central Kitchen's fresh, market-driven California cuisine to the fresh-made pastas from sister restaurant Flour + Water (which is currently closed for renovations). We loved the old Central Kitchen restaurant: the decor/ambiance is almost identical, and if you liked Central Kitchen's food, you'll find a lot to like here too. Food: The marinated squash & mushrooms were delicious although it might have worked better as a hot (versus cold) appetizer. The foccacia was crunchy and bursting with flavor. The tonnarelli cacio e pepe had a delicious sauce, although the pasta was a bit thicker & chewier than what you'd get in Rome. The seared trout was deliciously fatty and well-prepared, on some super-fresh greens with interesting accompaniments. Fregola Sarda was the only slight disappointment of the night; the flavors of the saffron and seafood were a bit overpowered by something acidic (vinegar?). Finally, the pomegranate and bay leaf sorbet was an outstanding dessert: the bay leaf complemented the pomegranate perfectly, adding an almost herbal minty-ness. Dietary restrictions: for a place with a heavy pasta emphasis, there are a fair number of gluten-free dishes (and dairy-free, with a few minor modifications) Kid friendliness: we brought our 5 year old, and although there is no "kids menu", they made a half-portion of pasta for him (he loved the cacio e pepe, although I suspect many kids would also like the bolognese), although his favorite thing was the foccacia Prices are reasonable considering the quality of the ingredients & cooking Getting in: book ahead (reservations open 2 weeks beforehand), sign up for last-minute openings on Resy, or arrive early for a walk-in spot (we arrived at 5 PM on a Sunday, and were 2nd in line for the 5:30 opening)

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05
Valencia Pizza & Pasta

Valencia Pizza & Pasta

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801 Valencia St, San Francisco, CA 94110, USA

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Matt Warren

What's not to like about solidly made, reasonably priced (for the nabe at least) and nicely presented pasta and pizza? Maybe you hate gluten or joy, or maybe you're too snobby for the plain-but-pleasing atmosphere, in which case you should go somewhere else, preferably far away, and stay there. Everyone else, check it out. There is also a quite good brunch, somewhat surprisingly for an Italian place.

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