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The 5 Best Gluten-Free American Restaurants in Downtown

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By Gluten Free Eats' gluten-free community

Updated Dec 2024

01
MacKenzie River Pizza, Grill & Pub

MacKenzie River Pizza, Grill & Pub

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Celiac friendly

120 W 11th St, Sioux Falls, SD 57104, USA

GF OptionsAmericanDeliveryDinnerKid FriendlyLunchOutdoor SeatingTake AwayVegetarian OptionsVegan OptionsPizzaCeliac FriendlyItalianOpen Late
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Nathan Bellis

The restaurant claims to accommodate allergies, but unfortunately, our gluten-free dish contained gluten, causing discomfort. I’d recommend extra caution with allergy labeling to ensure safety for all diners.

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Dedicated gluten-free menu
02
CRAVE American Kitchen & Sushi Bar (Hilton Garden Inn - Sioux Falls)

CRAVE American Kitchen & Sushi Bar (Hilton Garden Inn - Sioux Falls)

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Celiac friendly

201 E 8th St, Sioux Falls, SD 57103, USA

RestaurantGF OptionsBurgersOutdoor SeatingLocal CuisineAmericanSushiTake AwayIndoor SeatingDinnerLunchSeafoodBreakfastPizzaVegan FriendlySteakPoke BowlsWine BarCocktailsDeliveryOpen Late NightVegetarian OptionsBrunchKid FriendlyBarCeliac Friendly
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Jason Klawonn

It was a great experience! Arrived and ordered at 9:30 Friday evening. The staff was attentive and several checked if I'd been helped while a server was clearing a table. Ordered the Traditional Poke bowl and sake. It did take 30 minutes for the dish to come out, but it was a pleasant wait watching several people coming and going. Many gluten free options as well as vegetarian. Excellent food quality and the server was knowledgeable about the sake and food. Would definitely come back!

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Dedicated gluten-free menu
03
Blarney Stone Pub - Sioux Falls

Blarney Stone Pub - Sioux Falls

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Celiac friendly

333 S Phillips Ave, Sioux Falls, SD 57104, USA

GF OptionsBrunchDinnerKid FriendlyOpen Late NightLunchTake AwayBread ItemsBurgersCiderAmericanCeliac FriendlyDeliveryOutdoor Seating
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I basically got a Reuben burger off the gluten free menu with coleslaw and it was delicious!! My husband got buffalo wings with their homemade blue cheese- also delicious. Service was great, food came out fast. My only gripe is that their gluten free menu is very inaccurate and unless you really know what to look out for, you could cross contaminate yourself (though they give that disclaimer). A lot of the food on the gluten free menu is fried with other gluten foods so cross contamination is real. Thats why I ended up with the burger, but it was a great choice to end up with :)

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Dedicated gluten-free menu
04
Ode to Food and Drinks

Ode to Food and Drinks

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Gluten-free options

300 N Cherapa Pl, Sioux Falls, SD 57103, USA

LunchDinnerBrunchCafeAmericanTake AwayOutdoor SeatingKid FriendlyBar
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Nick Sampson

Food was really good, they had decent gluten free options. The server knew what was gluten free. My glasses all had lipstick marks. And every new glass they brought me also had them. Food was tasty, though my chislic came out cold. But everyone still seemed to like their meals. Also the creme brulee was good but burnt in the center. We just peeled the burnt part off and enjoyed the rest.

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GF options marked
05
Harvester Kitchen by Bryan

Harvester Kitchen by Bryan

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Gluten-free options

196 E 6th St Unit 101, Sioux Falls, SD 57104, USA

DinnerAmericanDeliveryTake AwayOutdoor SeatingKid FriendlyRestaurant
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BR14R (Gizmo Rx)

The "New Beginnings" prefix menu at this gem of an eatery was the culinary coup de grâce of my time in South Dakota. It began with a Red Thumb Potato Vichy that teased the palate with luxurious asian caviar, & progressed to an exquisite White Asparagus dish that was a celebration of texture and taste; my favorite. The Wild Alaskan Halibut followed, a delicate masterpiece complemented by the subtle spice of wild fennel. Lamb came next, with a sausage stuffed morel. To complete this gastronomic treat, the Creamsicle Cheesecake arrived as the sweetest of finales, a dessert so divine I must admit I love this place! Each course could be harmoniously paired with a fine wine selection. But I went for the eclectically balanced sour ale, which made my last evening one to remember, leaving me impressed, joyous, and delightfully sated. The service, as soon as I opened the door, exuded a helpful elegance and professionalism at a level never before experienced in this state! My mother said (in an inadvertently sent text with photo sent to me instead of her siblings), “Mom had a five-course meal tonight. Note the pillow behind her back! They were really helpful with getting her in, and the chef said goodbye to us at the door! Dean and I had a few crumbs, and they came with a crumb scraper. Very high-end! Caviar from Russia, asparagus from Holland, and halibut from Alaska! We had the right-side menu—delicious! 😋” From presentation to ambiance & from background stories to flavor profiles, to expertly executed celiac-safe gluten free variances…. This is a stand out establishment is downtown Sioux Falls. All my recommendations to this place!

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